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==X-ray structure of homo sapiens Fumarylacetoacetate hydrolase domain containing protein 1 (FAHD1) in complex with inhibitor oxalate at 1.94A resolution.==
==X-ray structure of homo sapiens Fumarylacetoacetate hydrolase domain containing protein 1 (FAHD1) in complex with inhibitor oxalate at 1.94A resolution.==
<StructureSection load='6fog' size='340' side='right' caption='[[6fog]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
<StructureSection load='6fog' size='340' side='right'caption='[[6fog]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6fog]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FOG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FOG FirstGlance]. <br>
<table><tr><td colspan='2'>[[6fog]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FOG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6FOG FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OXL:OXALATE+ION'>OXL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.94&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FAHD1, C16orf36, YISKL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OXL:OXALATE+ION'>OXL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fog FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fog OCA], [http://pdbe.org/6fog PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fog RCSB], [http://www.ebi.ac.uk/pdbsum/6fog PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fog ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6fog FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fog OCA], [https://pdbe.org/6fog PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6fog RCSB], [https://www.ebi.ac.uk/pdbsum/6fog PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6fog ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FAHD1_HUMAN FAHD1_HUMAN]] Probable mitochondrial acylpyruvase which is able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro.<ref>PMID:15551868</ref>
[https://www.uniprot.org/uniprot/FAHD1_HUMAN FAHD1_HUMAN] Probable mitochondrial acylpyruvase which is able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro.<ref>PMID:15551868</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Naschberger, A]]
[[Category: Large Structures]]
[[Category: Weiss, A K.H]]
[[Category: Naschberger A]]
[[Category: Fahd 1]]
[[Category: Weiss AKH]]
[[Category: Fumarylacetoacetate hydrolase domain containing protein 1]]
[[Category: Hydrolase-lyase complex]]
[[Category: Hydrolase/lyase]]
[[Category: Inhibitor]]
[[Category: Oxalate]]
Retrieved from "https://proteopedia.org/6fog"