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==QTRT2, the non-catalytic subunit of murine tRNA-Guanine Transglycosylase==
==QTRT2, the non-catalytic subunit of murine tRNA-Guanine Transglycosylase==
<StructureSection load='6fv5' size='340' side='right' caption='[[6fv5]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
<StructureSection load='6fv5' size='340' side='right'caption='[[6fv5]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6fv5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FV5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FV5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6fv5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FV5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6FV5 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.179&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Qtrt2, Qtrtd1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fv5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fv5 OCA], [http://pdbe.org/6fv5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fv5 RCSB], [http://www.ebi.ac.uk/pdbsum/6fv5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fv5 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6fv5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fv5 OCA], [https://pdbe.org/6fv5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6fv5 RCSB], [https://www.ebi.ac.uk/pdbsum/6fv5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6fv5 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/QTRT2_MOUSE QTRT2_MOUSE]] Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_03043]<ref>PMID:19414587</ref>
[https://www.uniprot.org/uniprot/QTRT2_MOUSE QTRT2_MOUSE] Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_03043]<ref>PMID:19414587</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6fv5" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6fv5" style="background-color:#fffaf0;"></div>
==See Also==
*[[TRNA-guanine transglycosylase 3D structures|TRNA-guanine transglycosylase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lk3 transgenic mice]]
[[Category: Large Structures]]
[[Category: Behrens, C]]
[[Category: Mus musculus]]
[[Category: Heine, A]]
[[Category: Behrens C]]
[[Category: Reuter, K]]
[[Category: Heine A]]
[[Category: Tim barrel]]
[[Category: Reuter K]]
[[Category: Transferase]]
[[Category: Transglycosylase]]
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