8jak: Difference between revisions
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==Human MCC in MCCU state== | |||
<StructureSection load='8jak' size='340' side='right'caption='[[8jak]], [[Resolution|resolution]] 2.52Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8jak]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8JAK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8JAK FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.52Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTI:5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL'>BTI</scene></td></tr> | ||
[[Category: Liu | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8jak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8jak OCA], [https://pdbe.org/8jak PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8jak RCSB], [https://www.ebi.ac.uk/pdbsum/8jak PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8jak ProSAT]</span></td></tr> | ||
[[Category: Su | </table> | ||
== Disease == | |||
[https://www.uniprot.org/uniprot/MCCB_HUMAN MCCB_HUMAN] 3-methylcrotonyl-CoA carboxylase deficiency. The disease is caused by variants affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MCCB_HUMAN MCCB_HUMAN] Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism.<ref>PMID:17360195</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Liu DS]] | |||
[[Category: Su JY]] | |||
[[Category: Tian XY]] | |||
