1xo3: Difference between revisions

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==Solution Structure of Ubiquitin like protein from Mus Musculus==
==Solution Structure of Ubiquitin like protein from Mus Musculus==
<StructureSection load='1xo3' size='340' side='right'caption='[[1xo3]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='1xo3' size='340' side='right'caption='[[1xo3]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1xo3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XO3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XO3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1xo3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XO3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XO3 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xo3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xo3 OCA], [https://pdbe.org/1xo3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xo3 RCSB], [https://www.ebi.ac.uk/pdbsum/1xo3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xo3 ProSAT], [https://www.topsan.org/Proteins/CESG/1xo3 TOPSAN]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xo3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xo3 OCA], [https://pdbe.org/1xo3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xo3 RCSB], [https://www.ebi.ac.uk/pdbsum/1xo3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xo3 ProSAT], [https://www.topsan.org/Proteins/CESG/1xo3 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/URM1_MOUSE URM1_MOUSE]] Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. May also act as an ubiquitin-like protein that is covalently conjugated to other proteins; the relevance of such function is however unclear in vivo (By similarity).  
[https://www.uniprot.org/uniprot/URM1_MOUSE URM1_MOUSE] Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. May also act as an ubiquitin-like protein that is covalently conjugated to other proteins; the relevance of such function is however unclear in vivo (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Bahrami, A]]
[[Category: Bahrami A]]
[[Category: Structural genomic]]
[[Category: Lee MS]]
[[Category: Lee, M S]]
[[Category: Markley JL]]
[[Category: Markley, J L]]
[[Category: Singh S]]
[[Category: Singh, S]]
[[Category: Tonelli M]]
[[Category: Tonelli, M]]
[[Category: Tyler RC]]
[[Category: Tyler, R C]]
[[Category: Cesg]]
[[Category: PSI, Protein structure initiative]]
[[Category: Unknown function]]