1zok: Difference between revisions
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==PDZ1 Domain Of Synapse Associated Protein 97== | ==PDZ1 Domain Of Synapse Associated Protein 97== | ||
<StructureSection load='1zok' size='340' side='right'caption='[[1zok | <StructureSection load='1zok' size='340' side='right'caption='[[1zok]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1zok]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1zok]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZOK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZOK FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zok FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zok OCA], [https://pdbe.org/1zok PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zok RCSB], [https://www.ebi.ac.uk/pdbsum/1zok PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zok ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zok FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zok OCA], [https://pdbe.org/1zok PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zok RCSB], [https://www.ebi.ac.uk/pdbsum/1zok PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zok ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/DLG1_RAT DLG1_RAT] Essential multidomain scaffolding protein required for normal development (By similarity). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. Regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels. Functional regulator of Kv1.5 channel (By similarity). May play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation.<ref>PMID:14960569</ref> <ref>PMID:15044483</ref> <ref>PMID:15504326</ref> <ref>PMID:19213956</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Rattus norvegicus]] | ||
[[Category: | [[Category: Mierke DF]] | ||
[[Category: | [[Category: Piserchio A]] | ||
[[Category: | [[Category: Wang L]] | ||