2abj: Difference between revisions
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<StructureSection load='2abj' size='340' side='right'caption='[[2abj]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='2abj' size='340' side='right'caption='[[2abj]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2abj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2abj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ABJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ABJ FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CBC:N-(5-CHLOROBENZOFURAN-2-CARBONYL)-2-(TRIFLUOROMETHYL)BENZENESULFONOHYDRAZIDE'>CBC</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2abj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2abj OCA], [https://pdbe.org/2abj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2abj RCSB], [https://www.ebi.ac.uk/pdbsum/2abj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2abj ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2abj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2abj OCA], [https://pdbe.org/2abj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2abj RCSB], [https://www.ebi.ac.uk/pdbsum/2abj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2abj ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/BCAT1_HUMAN BCAT1_HUMAN] Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Hasemann | [[Category: Hasemann CH]] | ||
[[Category: Hu | [[Category: Hu HL]] | ||
[[Category: McConnell | [[Category: McConnell PC]] | ||
[[Category: Mistry | [[Category: Mistry A]] | ||
[[Category: Moreland | [[Category: Moreland DW]] | ||
[[Category: Mueller | [[Category: Mueller WT]] | ||
[[Category: Ohren | [[Category: Ohren JF]] | ||
[[Category: Rubin | [[Category: Rubin JR]] | ||
[[Category: Scholten | [[Category: Scholten JD]] | ||
Revision as of 08:16, 15 May 2024
Crystal structure of human branched chain amino acid transaminase in a complex with an inhibitor, C16H10N2O4F3SCl, and pyridoxal 5' phosphate.
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