8uo9: Difference between revisions

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'''Unreleased structure'''


The entry 8uo9 is ON HOLD  until Paper Publication
==Structure of synaptic vesicle protein 2A in complex with a nanobody==
 
<StructureSection load='8uo9' size='340' side='right'caption='[[8uo9]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8uo9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Lama_glama Lama glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8UO9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8UO9 FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PS1:1,2-DIDECANOYL-SN-GLYCERO-3-[PHOSPHO-L-SERINE]'>PS1</scene>, <scene name='pdbligand=X49:(4R)-1-{[(4S)-2-(methoxymethyl)-6-(trifluoromethyl)imidazo[2,1-b][1,3,4]thiadiazol-5-yl]methyl}-4-(4,4,4-trifluorobutyl)pyrrolidin-2-one'>X49</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8uo9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8uo9 OCA], [https://pdbe.org/8uo9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8uo9 RCSB], [https://www.ebi.ac.uk/pdbsum/8uo9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8uo9 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SV2A_HUMAN SV2A_HUMAN] Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity).
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Lama glama]]
[[Category: Large Structures]]
[[Category: Adams C]]
[[Category: Coleman JA]]
[[Category: Horyani PS]]
[[Category: Ledecq M]]
[[Category: Levin E]]
[[Category: Martin MF]]
[[Category: Mittal A]]
[[Category: Yang M]]