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==NMR structural analysis of Nop10p from Saccharomyces cerevisiae==
==NMR structural analysis of Nop10p from Saccharomyces cerevisiae==
<StructureSection load='2aqa' size='340' side='right'caption='[[2aqa]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2aqa' size='340' side='right'caption='[[2aqa]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2aqa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AQA FirstGlance]. <br>
<table><tr><td colspan='2'>[[2aqa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AQA FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NOP10 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2aqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aqa OCA], [https://pdbe.org/2aqa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2aqa RCSB], [https://www.ebi.ac.uk/pdbsum/2aqa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2aqa ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2aqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aqa OCA], [https://pdbe.org/2aqa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2aqa RCSB], [https://www.ebi.ac.uk/pdbsum/2aqa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2aqa ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/NOP10_YEAST NOP10_YEAST]] Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. Essential for growth.<ref>PMID:9843512</ref>
[https://www.uniprot.org/uniprot/NOP10_YEAST NOP10_YEAST] Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. Essential for growth.<ref>PMID:9843512</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 18824]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Amare, A R.Ferre-D]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Hamma, T]]
[[Category: Ferre-D'Amare AR]]
[[Category: Reichow, S L]]
[[Category: Hamma T]]
[[Category: Varani, G]]
[[Category: Reichow SL]]
[[Category: Nop10p]]
[[Category: Varani G]]
[[Category: Rna binding protein]]
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