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==SOLUTION STRUCTURE OF A CALMODULIN-TARGET PEPTIDE COMPLEX BY MULTIDIMENSIONAL NMR==
==SOLUTION STRUCTURE OF A CALMODULIN-TARGET PEPTIDE COMPLEX BY MULTIDIMENSIONAL NMR==
<StructureSection load='2bbn' size='340' side='right'caption='[[2bbn]], [[NMR_Ensembles_of_Models | 21 NMR models]]' scene=''>
<StructureSection load='2bbn' size='340' side='right'caption='[[2bbn]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2bbn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drome Drome]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BBN FirstGlance]. <br>
<table><tr><td colspan='2'>[[2bbn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster] and [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BBN FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2bbm|2bbm]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bbn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bbn OCA], [https://pdbe.org/2bbn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bbn RCSB], [https://www.ebi.ac.uk/pdbsum/2bbn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bbn ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bbn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bbn OCA], [https://pdbe.org/2bbn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bbn RCSB], [https://www.ebi.ac.uk/pdbsum/2bbn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bbn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/CALM_DROME CALM_DROME]] Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. [[https://www.uniprot.org/uniprot/MYLK2_RABIT MYLK2_RABIT]] Implicated in the level of global muscle contraction and cardiac function (By similarity). Phosphorylates a specific serine in the N-terminus of a myosin light chain.  
[https://www.uniprot.org/uniprot/CALM_DROME CALM_DROME] Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Drome]]
[[Category: Drosophila melanogaster]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Bax, A]]
[[Category: Oryctolagus cuniculus]]
[[Category: Clore, G M]]
[[Category: Bax A]]
[[Category: Gronenborn, A M]]
[[Category: Clore GM]]
[[Category: Ikura, M]]
[[Category: Gronenborn AM]]
[[Category: Calcium-binding protein]]
[[Category: Ikura M]]
Retrieved from "https://proteopedia.org/2bbn"