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==SOLUTION NMR STRUCTURE OF THE L22V MUTANT DNA BINDING DOMAIN OF AREA COMPLEXED TO A 13 BP DNA CONTAINING A TGATA SITE, REGULARIZED MEAN STRUCTURE==
==SOLUTION NMR STRUCTURE OF THE L22V MUTANT DNA BINDING DOMAIN OF AREA COMPLEXED TO A 13 BP DNA CONTAINING A TGATA SITE, REGULARIZED MEAN STRUCTURE==
<StructureSection load='6gat' size='340' side='right'caption='[[6gat]], [[NMR_Ensembles_of_Models | 1 NMR models]]' scene=''>
<StructureSection load='6gat' size='340' side='right'caption='[[6gat]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6gat]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/A._nidulans A. nidulans]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GAT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6GAT FirstGlance]. <br>
<table><tr><td colspan='2'>[[6gat]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_nidulans Aspergillus nidulans]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GAT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6GAT FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[7gat|7gat]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">POTENTIAL ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=162425 A. nidulans])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6gat FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gat OCA], [https://pdbe.org/6gat PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6gat RCSB], [https://www.ebi.ac.uk/pdbsum/6gat PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6gat ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6gat FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gat OCA], [https://pdbe.org/6gat PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6gat RCSB], [https://www.ebi.ac.uk/pdbsum/6gat PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6gat ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/AREA_EMENI AREA_EMENI]] Transcription activator that binds the consensus DNA element 5'-CGATAG-3' and mediates nitrogen metabolite repression. Activates the transcription of uapA.<ref>PMID:1970293</ref>
[https://www.uniprot.org/uniprot/AREA_EMENI AREA_EMENI] Transcription activator that binds the consensus DNA element 5'-CGATAG-3' and mediates nitrogen metabolite repression. Activates the transcription of uapA.<ref>PMID:1970293</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: A. nidulans]]
[[Category: Aspergillus nidulans]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Clore, G M]]
[[Category: Clore GM]]
[[Category: Gronenborn, A M]]
[[Category: Gronenborn AM]]
[[Category: Starich, M]]
[[Category: Starich M]]
[[Category: Wikstrom, M]]
[[Category: Wikstrom M]]
[[Category: Dna binding protein]]
[[Category: Transcription factor]]
[[Category: Transcription-dna complex]]
[[Category: Zinc binding domain]]
Retrieved from "https://proteopedia.org/6gat"