6rtf: Difference between revisions

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<SX load='6rtf' size='340' side='right' viewer='molstar' caption='[[6rtf]], [[Resolution|resolution]] 7.77&Aring;' scene=''>
<SX load='6rtf' size='340' side='right' viewer='molstar' caption='[[6rtf]], [[Resolution|resolution]] 7.77&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6rtf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RTF OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6RTF FirstGlance]. <br>
<table><tr><td colspan='2'>[[6rtf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RTF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RTF FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6rtc|6rtc]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 7.77&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Slc26a9, mCG_51751 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rtf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rtf OCA], [https://pdbe.org/6rtf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rtf RCSB], [https://www.ebi.ac.uk/pdbsum/6rtf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rtf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6rtf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rtf OCA], [http://pdbe.org/6rtf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rtf RCSB], [http://www.ebi.ac.uk/pdbsum/6rtf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rtf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/A0A0R4J0F7_MOUSE A0A0R4J0F7_MOUSE]] DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport.[RuleBase:RU362052]
[https://www.uniprot.org/uniprot/S26A9_MOUSE S26A9_MOUSE] DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport (PubMed:15800055, PubMed:17120765). Mediates chloride/bicarbonate exchange or chloride-independent bicarbonate extrusion thus assuring bicarbonate secretion (PubMed:15800055, PubMed:17120765). May prefer chloride anions and mediate uncoupled chloride anion transport in an alternate-access mechanism where a saturable binding site is alternately exposed to either one or the other side of the membrane (PubMed:31339488).<ref>PMID:15800055</ref> <ref>PMID:17120765</ref> <ref>PMID:31339488</ref>
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Dutzler, R]]
[[Category: Dutzler R]]
[[Category: Sawicka, M]]
[[Category: Sawicka M]]
[[Category: Walter, J D]]
[[Category: Walter JD]]
[[Category: Anion transporter]]
[[Category: Cryo-em]]
[[Category: Membrane protein]]
[[Category: Membrane protein structure]]
[[Category: Single particle]]
[[Category: Slc26 family]]
[[Category: Transport mechanism]]