6wfv: Difference between revisions

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<StructureSection load='6wfv' size='340' side='right'caption='[[6wfv]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='6wfv' size='340' side='right'caption='[[6wfv]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6wfv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WFV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WFV FirstGlance]. <br>
<table><tr><td colspan='2'>[[6wfv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WFV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WFV FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PLOD3 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wfv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wfv OCA], [https://pdbe.org/6wfv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wfv RCSB], [https://www.ebi.ac.uk/pdbsum/6wfv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wfv ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wfv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wfv OCA], [https://pdbe.org/6wfv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wfv RCSB], [https://www.ebi.ac.uk/pdbsum/6wfv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wfv ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
[[https://www.uniprot.org/uniprot/PLOD3_HUMAN PLOD3_HUMAN]] Connective tissue disorder due to lysyl hydroxylase-3 deficiency. The disease is caused by mutations affecting the gene represented in this entry.  
[https://www.uniprot.org/uniprot/PLOD3_HUMAN PLOD3_HUMAN] Connective tissue disorder due to lysyl hydroxylase-3 deficiency. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/PLOD3_HUMAN PLOD3_HUMAN]] Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.[UniProtKB:P24802]  
[https://www.uniprot.org/uniprot/PLOD3_HUMAN PLOD3_HUMAN] Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.[UniProtKB:P24802]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Guo, H F]]
[[Category: Guo H-F]]
[[Category: Kurie, J M]]
[[Category: Kurie JM]]
[[Category: Miller, M D]]
[[Category: Miller MD]]
[[Category: Phillips, G N]]
[[Category: Phillips Jr GN]]
[[Category: Tainer, J A]]
[[Category: Tainer JA]]
[[Category: Tsai, C L]]
[[Category: Tsai C-L]]
[[Category: Magnesium]]
[[Category: Manganese]]
[[Category: Rossmann fold]]
[[Category: Transferase]]
[[Category: Udp]]
Retrieved from "https://proteopedia.org/6wfv"