1sa4: Difference between revisions

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[[Image:1sa4.gif|left|200px]]
[[Image:1sa4.gif|left|200px]]


{{Structure
<!--
|PDB= 1sa4 |SIZE=350|CAPTION= <scene name='initialview01'>1sa4</scene>, resolution 2.10&Aring;
The line below this paragraph, containing "STRUCTURE_1sa4", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
|LIGAND= <scene name='pdbligand=FPP:FARNESYL+DIPHOSPHATE'>FPP</scene>, <scene name='pdbligand=JAN:6-[(S)-AMINO(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]-4-(3-CHLOROPHENYL)-1-METHYLQUINOLIN-2(1H)-ONE'>JAN</scene>, <scene name='pdbligand=SUC:SUCROSE'>SUC</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein_farnesyltransferase Protein farnesyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.58 2.5.1.58] </span>
or leave the SCENE parameter empty for the default display.
|GENE= FNTA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), FNTB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
-->
|DOMAIN=
{{STRUCTURE_1sa4|  PDB=1sa4 |  SCENE= }}  
|RELATEDENTRY=[[1d8d|1D8D]], [[1ft1|1FT1]], [[1jcq|1JCQ]], [[1jcr|1JCR]], [[1o5m|1O5M]], [[1ld8|1LD8]], [[1sa5|1SA5]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sa4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sa4 OCA], [http://www.ebi.ac.uk/pdbsum/1sa4 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1sa4 RCSB]</span>
}}


'''human protein farnesyltransferase complexed with FPP and R115777'''
'''human protein farnesyltransferase complexed with FPP and R115777'''
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[[Category: Beese, L S.]]
[[Category: Beese, L S.]]
[[Category: Reid, T S.]]
[[Category: Reid, T S.]]
[[Category: caax]]
[[Category: Caax]]
[[Category: cancer]]
[[Category: Cancer]]
[[Category: clinical candidate]]
[[Category: Clinical candidate]]
[[Category: farnesyl transferase]]
[[Category: Farnesyl transferase]]
[[Category: farnesyltransferase]]
[[Category: Farnesyltransferase]]
[[Category: ftase]]
[[Category: Ftase]]
[[Category: fti]]
[[Category: Fti]]
[[Category: inhibitor]]
[[Category: Inhibitor]]
[[Category: lipid modification]]
[[Category: Lipid modification]]
[[Category: protein prenylation]]
[[Category: Protein prenylation]]
[[Category: r115777]]
[[Category: R115777]]
[[Category: ra]]
[[Category: Ra]]
[[Category: tipifarnib]]
[[Category: Tipifarnib]]
[[Category: tumor regression]]
[[Category: Tumor regression]]
[[Category: zarnestra]]
[[Category: Zarnestra]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 08:28:37 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:39:18 2008''
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