2d7l: Difference between revisions
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==Solution structure of the HMG box domain from human WD repeat and HMG-box DNA binding protein 1== | ==Solution structure of the HMG box domain from human WD repeat and HMG-box DNA binding protein 1== | ||
<StructureSection load='2d7l' size='340' side='right'caption='[[2d7l | <StructureSection load='2d7l' size='340' side='right'caption='[[2d7l]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2d7l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2d7l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D7L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D7L FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d7l OCA], [https://pdbe.org/2d7l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d7l RCSB], [https://www.ebi.ac.uk/pdbsum/2d7l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d7l ProSAT], [https://www.topsan.org/Proteins/RSGI/2d7l TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d7l OCA], [https://pdbe.org/2d7l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d7l RCSB], [https://www.ebi.ac.uk/pdbsum/2d7l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d7l ProSAT], [https://www.topsan.org/Proteins/RSGI/2d7l TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/WDHD1_HUMAN WDHD1_HUMAN] Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication.<ref>PMID:19805216</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Inoue | [[Category: Inoue M]] | ||
[[Category: Kamatari | [[Category: Kamatari YO]] | ||
[[Category: Kigawa | [[Category: Kigawa T]] | ||
[[Category: Koshiba | [[Category: Koshiba S]] | ||
[[Category: Saito K]] | |||
[[Category: Saito | [[Category: Tomizawa T]] | ||
[[Category: Tomizawa | [[Category: Yokoyama S]] | ||
[[Category: Yokoyama | |||
Latest revision as of 11:34, 22 May 2024
Solution structure of the HMG box domain from human WD repeat and HMG-box DNA binding protein 1
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