2dha: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Solution structure of the second RNA recognition motif in Hypothetical protein FLJ201171== | ==Solution structure of the second RNA recognition motif in Hypothetical protein FLJ201171== | ||
<StructureSection load='2dha' size='340' side='right'caption='[[2dha | <StructureSection load='2dha' size='340' side='right'caption='[[2dha]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2dha]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2dha]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DHA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DHA FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dha FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dha OCA], [https://pdbe.org/2dha PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dha RCSB], [https://www.ebi.ac.uk/pdbsum/2dha PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dha ProSAT], [https://www.topsan.org/Proteins/RSGI/2dha TOPSAN]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dha FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dha OCA], [https://pdbe.org/2dha PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dha RCSB], [https://www.ebi.ac.uk/pdbsum/2dha PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dha ProSAT], [https://www.topsan.org/Proteins/RSGI/2dha TOPSAN]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/ESRP1_HUMAN ESRP1_HUMAN] mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 20: | Line 21: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Imai | [[Category: Imai T]] | ||
[[Category: Inoue | [[Category: Inoue M]] | ||
[[Category: Kigawa | [[Category: Kigawa T]] | ||
[[Category: Muto | [[Category: Muto Y]] | ||
[[Category: Shirouzu M]] | |||
[[Category: Shirouzu | [[Category: Terada T]] | ||
[[Category: Terada | [[Category: Tsuda K]] | ||
[[Category: Tsuda | [[Category: Yokoyama S]] | ||
[[Category: Yokoyama | |||
Latest revision as of 11:38, 22 May 2024
Solution structure of the second RNA recognition motif in Hypothetical protein FLJ201171
| ||||||||||||
