2dmy: Difference between revisions
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==Solution structure of DSRM domain in Spermatid perinuclear RNA-bind protein== | ==Solution structure of DSRM domain in Spermatid perinuclear RNA-bind protein== | ||
<StructureSection load='2dmy' size='340' side='right'caption='[[2dmy | <StructureSection load='2dmy' size='340' side='right'caption='[[2dmy]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2dmy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2dmy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DMY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DMY FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dmy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dmy OCA], [https://pdbe.org/2dmy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dmy RCSB], [https://www.ebi.ac.uk/pdbsum/2dmy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dmy ProSAT], [https://www.topsan.org/Proteins/RSGI/2dmy TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dmy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dmy OCA], [https://pdbe.org/2dmy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dmy RCSB], [https://www.ebi.ac.uk/pdbsum/2dmy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dmy ProSAT], [https://www.topsan.org/Proteins/RSGI/2dmy TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/STRBP_HUMAN STRBP_HUMAN] Involved in spermatogenesis and sperm function. Plays a role in regulation of cell growth. Binds to double-stranded DNA and RNA. Binds most efficiently to poly(I:C) RNA than to poly(dI:dC) DNA. Binds also to single-stranded poly(G) RNA. Binds non-specifically to the mRNA PRM1 3'-UTR and adenovirus VA RNA (By similarity). | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: He | [[Category: He F]] | ||
[[Category: Inoue | [[Category: Inoue M]] | ||
[[Category: Kadirvel | [[Category: Kadirvel S]] | ||
[[Category: Kigawa | [[Category: Kigawa T]] | ||
[[Category: Muto | [[Category: Muto Y]] | ||
[[Category: Shirouzu M]] | |||
[[Category: Shirouzu | [[Category: Terada T]] | ||
[[Category: Terada | [[Category: Yokoyama S]] | ||
[[Category: Yokoyama | |||
