2ebu: Difference between revisions

<StructureSection load='2ebu' size='340' side='right'caption='[[2ebu]]' scene=''>

<table><tr><td colspan='2'>[[2ebu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EBU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EBU FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ebu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ebu OCA], [https://pdbe.org/2ebu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ebu RCSB], [https://www.ebi.ac.uk/pdbsum/2ebu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ebu ProSAT], [https://www.topsan.org/Proteins/RSGI/2ebu TOPSAN]</span></td></tr>

[https://www.uniprot.org/uniprot/RFC1_HUMAN RFC1_HUMAN] The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1. This subunit binds to the primer-template junction. Binds the PO-B transcription element as well as other GA rich DNA sequences. Could play a role in DNA transcription regulation as well as DNA replication and/or repair. Can bind single- or double-stranded DNA.<ref>PMID:8999859</ref>  Interacts with C-terminus of PCNA. 5' phosphate residue is required for binding of the N-terminal DNA-binding domain to duplex DNA, suggesting a role in recognition of non-primer template DNA structures during replication and/or repair.<ref>PMID:8999859</ref>  

[[Category: Homo sapiens]]

[[Category: Hayashi F]]

[[Category: Nagashima T]]

[[Category: Yokoyama S]]