2ecb: Difference between revisions
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==The solution structure of the third homeobox domain of human zinc fingers and homeoboxes protein== | ==The solution structure of the third homeobox domain of human zinc fingers and homeoboxes protein== | ||
<StructureSection load='2ecb' size='340' side='right'caption='[[2ecb | <StructureSection load='2ecb' size='340' side='right'caption='[[2ecb]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ecb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2ecb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2djo 2djo]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ECB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ECB FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ecb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ecb OCA], [https://pdbe.org/2ecb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ecb RCSB], [https://www.ebi.ac.uk/pdbsum/2ecb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ecb ProSAT], [https://www.topsan.org/Proteins/RSGI/2ecb TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ecb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ecb OCA], [https://pdbe.org/2ecb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ecb RCSB], [https://www.ebi.ac.uk/pdbsum/2ecb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ecb ProSAT], [https://www.topsan.org/Proteins/RSGI/2ecb TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/ZHX1_HUMAN ZHX1_HUMAN] Acts as a transcriptional repressor. Increases DNMT3B-mediated repressive transcriptional activity when DNMT3B is tethered to DNA. May link molecule between DNMT3B and other co-repressor proteins.<ref>PMID:12237128</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Inoue | [[Category: Inoue M]] | ||
[[Category: Kigawa | [[Category: Kigawa T]] | ||
[[Category: Koshiba | [[Category: Koshiba S]] | ||
[[Category: Ohnishi | [[Category: Ohnishi S]] | ||
[[Category: Saito K]] | |||
[[Category: Saito | [[Category: Sasagawa A]] | ||
[[Category: Sasagawa | [[Category: Tochio N]] | ||
[[Category: Tochio | [[Category: Yokoyama S]] | ||
[[Category: Yokoyama | |||
Latest revision as of 18:49, 29 May 2024
The solution structure of the third homeobox domain of human zinc fingers and homeoboxes protein
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