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==Solution structure of RUH-075, a human CUE domain==
==Solution structure of RUH-075, a human CUE domain==
<StructureSection load='2ekf' size='340' side='right'caption='[[2ekf]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2ekf' size='340' side='right'caption='[[2ekf]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ekf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EKF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EKF FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ekf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EKF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EKF FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ekf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ekf OCA], [https://pdbe.org/2ekf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ekf RCSB], [https://www.ebi.ac.uk/pdbsum/2ekf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ekf ProSAT], [https://www.topsan.org/Proteins/RSGI/2ekf TOPSAN]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ekf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ekf OCA], [https://pdbe.org/2ekf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ekf RCSB], [https://www.ebi.ac.uk/pdbsum/2ekf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ekf ProSAT], [https://www.topsan.org/Proteins/RSGI/2ekf TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/AUP1_HUMAN AUP1_HUMAN]] May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome.<ref>PMID:18711132</ref>
[https://www.uniprot.org/uniprot/AUP1_HUMAN AUP1_HUMAN] May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome.<ref>PMID:18711132</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Hayashi, F]]
[[Category: Hayashi F]]
[[Category: Hirota, H]]
[[Category: Hirota H]]
[[Category: Momen, A Z.M Ruhul]]
[[Category: Ruhul Momen AZM]]
[[Category: Structural genomic]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S]]
[[Category: Cue]]
[[Category: Ligase]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Rsgi]]
[[Category: Ubiquitin ligase complex]]
[[Category: Ubiquitin-conjugating enzyme]]
Retrieved from "https://proteopedia.org/2ekf"