2els: Difference between revisions
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==Solution structure of the 2nd C2H2 zinc finger of human Zinc finger protein 406== | ==Solution structure of the 2nd C2H2 zinc finger of human Zinc finger protein 406== | ||
<StructureSection load='2els' size='340' side='right'caption='[[2els | <StructureSection load='2els' size='340' side='right'caption='[[2els]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2els]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2els]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ELS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ELS FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2els FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2els OCA], [https://pdbe.org/2els PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2els RCSB], [https://www.ebi.ac.uk/pdbsum/2els PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2els ProSAT], [https://www.topsan.org/Proteins/RSGI/2els TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2els FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2els OCA], [https://pdbe.org/2els PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2els RCSB], [https://www.ebi.ac.uk/pdbsum/2els PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2els ProSAT], [https://www.topsan.org/Proteins/RSGI/2els TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/ZFAT_HUMAN ZFAT_HUMAN] May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity). | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Harada | [[Category: Harada T]] | ||
[[Category: Kigawa | [[Category: Kigawa T]] | ||
[[Category: Koshiba | [[Category: Koshiba S]] | ||
[[Category: Tanaka A]] | |||
[[Category: Tanaka | [[Category: Tochio N]] | ||
[[Category: Tochio | [[Category: Umehara T]] | ||
[[Category: Umehara | [[Category: Watanabe S]] | ||
[[Category: Watanabe | [[Category: Yokoyama S]] | ||
[[Category: Yokoyama | [[Category: Yoneyama M]] | ||
[[Category: Yoneyama | |||