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==Solution structure of the SCAN homodimer from MZF-1/ZNF42==
==Solution structure of the SCAN homodimer from MZF-1/ZNF42==
<StructureSection load='2fi2' size='340' side='right'caption='[[2fi2]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2fi2' size='340' side='right'caption='[[2fi2]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2fi2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FI2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FI2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2fi2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FI2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FI2 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ZNF42, MZF1, ZSCAN6 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fi2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fi2 OCA], [https://pdbe.org/2fi2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fi2 RCSB], [https://www.ebi.ac.uk/pdbsum/2fi2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fi2 ProSAT], [https://www.topsan.org/Proteins/CESG/2fi2 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fi2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fi2 OCA], [https://pdbe.org/2fi2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fi2 RCSB], [https://www.ebi.ac.uk/pdbsum/2fi2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fi2 ProSAT], [https://www.topsan.org/Proteins/CESG/2fi2 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/MZF1_HUMAN MZF1_HUMAN]] Binds to target promoter DNA and functions as trancription regulator. Regulates transcription from the PADI1 and CDH2 promoter. May be one regulator of transcriptional events during hemopoietic development.<ref>PMID:15541732</ref> <ref>PMID:17851584</ref>
[https://www.uniprot.org/uniprot/MZF1_HUMAN MZF1_HUMAN] Binds to target promoter DNA and functions as trancription regulator. Regulates transcription from the PADI1 and CDH2 promoter. May be one regulator of transcriptional events during hemopoietic development.<ref>PMID:15541732</ref> <ref>PMID:17851584</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Structural genomic]]
[[Category: Peterson FC]]
[[Category: Peterson, F C]]
[[Category: Sander TL]]
[[Category: Sander, T L]]
[[Category: Volkman BF]]
[[Category: Volkman, B F]]
[[Category: Waltner JK]]
[[Category: Waltner, J K]]
[[Category: Cesg]]
[[Category: Homodimer]]
[[Category: Mzf-1]]
[[Category: PSI, Protein structure initiative]]
[[Category: Scan domain]]
[[Category: Transcription]]
[[Category: Transcription factor]]
[[Category: Znf-42]]
Retrieved from "https://proteopedia.org/2fi2"