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==Solution structure of Murine p22HBP==
==Solution structure of Murine p22HBP==
<StructureSection load='2gov' size='340' side='right'caption='[[2gov]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2gov' size='340' side='right'caption='[[2gov]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2gov]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GOV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GOV FirstGlance]. <br>
<table><tr><td colspan='2'>[[2gov]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GOV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GOV FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Hebp1, Hbp ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gov FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gov OCA], [https://pdbe.org/2gov PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gov RCSB], [https://www.ebi.ac.uk/pdbsum/2gov PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gov ProSAT], [https://www.topsan.org/Proteins/CESG/2gov TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gov FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gov OCA], [https://pdbe.org/2gov PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gov RCSB], [https://www.ebi.ac.uk/pdbsum/2gov PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gov ProSAT], [https://www.topsan.org/Proteins/CESG/2gov TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/HEBP1_MOUSE HEBP1_MOUSE]] May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of heme or porphyrins. It binds metalloporphyrins, free porphyrins and N-methylprotoporphyrin with similar affinities.<ref>PMID:12413491</ref> <ref>PMID:16905545</ref>
[https://www.uniprot.org/uniprot/HEBP1_MOUSE HEBP1_MOUSE] May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of heme or porphyrins. It binds metalloporphyrins, free porphyrins and N-methylprotoporphyrin with similar affinities.<ref>PMID:12413491</ref> <ref>PMID:16905545</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Structural genomic]]
[[Category: Dias JS]]
[[Category: Dias, J S]]
[[Category: Goodfellow BJ]]
[[Category: Goodfellow, B J]]
[[Category: Peterson FC]]
[[Category: Peterson, F C]]
[[Category: Volkman BF]]
[[Category: Volkman, B F]]
[[Category: Cesg]]
[[Category: Heme binding]]
[[Category: Heme binding protein]]
[[Category: P22hbp]]
[[Category: PSI, Protein structure initiative]]
Retrieved from "https://proteopedia.org/2gov"