2k00: Difference between revisions

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==Solution structure of the talin F3 in complex with layilin cytodomain==
==Solution structure of the talin F3 in complex with layilin cytodomain==
<StructureSection load='2k00' size='340' side='right'caption='[[2k00]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2k00' size='340' side='right'caption='[[2k00]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2k00]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K00 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K00 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2k00]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K00 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K00 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TLN1, TLN ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 Gallus gallus])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k00 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k00 OCA], [https://pdbe.org/2k00 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k00 RCSB], [https://www.ebi.ac.uk/pdbsum/2k00 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k00 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k00 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k00 OCA], [https://pdbe.org/2k00 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k00 RCSB], [https://www.ebi.ac.uk/pdbsum/2k00 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k00 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/TLN1_CHICK TLN1_CHICK]] Probably involved in connections of major cytoskeletal structures to the plasma membrane. Talin is a high molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts. [[https://www.uniprot.org/uniprot/LAYN_MOUSE LAYN_MOUSE]] Receptor for hyaluronate (By similarity).  
[https://www.uniprot.org/uniprot/TLN1_CHICK TLN1_CHICK] Probably involved in connections of major cytoskeletal structures to the plasma membrane. Talin is a high molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Talin|Talin]]
*[[Talin 3D structures|Talin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Barsukov, I L]]
[[Category: Mus musculus]]
[[Category: Wegener, K L]]
[[Category: Barsukov IL]]
[[Category: Alternative splicing]]
[[Category: Wegener KL]]
[[Category: Cell projection]]
[[Category: Cytoplasm]]
[[Category: Cytoskeleton]]
[[Category: Glycoprotein]]
[[Category: Lectin]]
[[Category: Membrane]]
[[Category: Phosphoprotein]]
[[Category: Structural protein]]
[[Category: Transmembrane]]