2k3k: Difference between revisions

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==Solution structure of Drosophila melanogaster SNF RBD1==
==Solution structure of Drosophila melanogaster SNF RBD1==
<StructureSection load='2k3k' size='340' side='right'caption='[[2k3k]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2k3k' size='340' side='right'caption='[[2k3k]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2k3k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2fjj 2fjj]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K3K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K3K FirstGlance]. <br>
<table><tr><td colspan='2'>[[2k3k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2fjj 2fjj]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K3K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K3K FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k3k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k3k OCA], [https://pdbe.org/2k3k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k3k RCSB], [https://www.ebi.ac.uk/pdbsum/2k3k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k3k ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k3k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k3k OCA], [https://pdbe.org/2k3k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k3k RCSB], [https://www.ebi.ac.uk/pdbsum/2k3k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k3k ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/SNRPA_DROME SNRPA_DROME]] Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP (By similarity). Plays a role in regulating sex-lethal splicing.  
[https://www.uniprot.org/uniprot/SNRPA_DROME SNRPA_DROME] Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP (By similarity). Plays a role in regulating sex-lethal splicing.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Cui, G]]
[[Category: Cui G]]
[[Category: Hu, J]]
[[Category: Hu J]]
[[Category: Jin, C]]
[[Category: Jin C]]
[[Category: Liu, C]]
[[Category: Liu C]]
[[Category: Xia, B]]
[[Category: Xia B]]
[[Category: Mrna processing]]
[[Category: Mrna splicing]]
[[Category: Nucleus]]
[[Category: Ribonucleoprotein]]
[[Category: Rna binding]]
[[Category: Rna binding protein]]
[[Category: Rna splicing]]
[[Category: Rna-binding]]
[[Category: Snf rbd1]]
[[Category: Solution structure]]
[[Category: Spliceosome]]

Latest revision as of 19:09, 29 May 2024

Solution structure of Drosophila melanogaster SNF RBD1

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