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==NMR structure of the F1 domain (residues 86-202) of the talin==
==NMR structure of the F1 domain (residues 86-202) of the talin==
<StructureSection load='2kc2' size='340' side='right'caption='[[2kc2]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
<StructureSection load='2kc2' size='340' side='right'caption='[[2kc2]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2kc2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KC2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KC2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2kc2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KC2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KC2 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2kc1|2kc1]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Tln, Tln1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kc2 OCA], [https://pdbe.org/2kc2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kc2 RCSB], [https://www.ebi.ac.uk/pdbsum/2kc2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kc2 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kc2 OCA], [https://pdbe.org/2kc2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kc2 RCSB], [https://www.ebi.ac.uk/pdbsum/2kc2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kc2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/TLN1_MOUSE TLN1_MOUSE]] Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts.  
[https://www.uniprot.org/uniprot/TLN1_MOUSE TLN1_MOUSE] Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Talin|Talin]]
*[[Talin 3D structures|Talin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Barsukov, I L]]
[[Category: Barsukov IL]]
[[Category: Critchely, D R]]
[[Category: Critchely DR]]
[[Category: Elliott, P R]]
[[Category: Elliott PR]]
[[Category: Goult, B T]]
[[Category: Goult BT]]
[[Category: Roberts, G C.K]]
[[Category: Roberts GCK]]
[[Category: Adhesion]]
[[Category: Cell membrane]]
[[Category: Cell projection]]
[[Category: Cytoplasm]]
[[Category: Cytoskeleton]]
[[Category: F1]]
[[Category: Ferm]]
[[Category: Membrane]]
[[Category: Phosphoprotein]]
[[Category: Structural protein]]
[[Category: Talin]]
Retrieved from "https://proteopedia.org/2kc2"