2rqq: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
 
Line 1: Line 1:


==Structure of C-terminal region of Cdt1==
==Structure of C-terminal region of Cdt1==
<StructureSection load='2rqq' size='340' side='right'caption='[[2rqq]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2rqq' size='340' side='right'caption='[[2rqq]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2rqq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RQQ FirstGlance]. <br>
<table><tr><td colspan='2'>[[2rqq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RQQ FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cdt1, Ris2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rqq OCA], [https://pdbe.org/2rqq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rqq RCSB], [https://www.ebi.ac.uk/pdbsum/2rqq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rqq ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rqq OCA], [https://pdbe.org/2rqq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rqq RCSB], [https://www.ebi.ac.uk/pdbsum/2rqq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rqq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/CDT1_MOUSE CDT1_MOUSE]] Cooperates with CDC6 to promote the loading of the mini-chromosome maintenance complex onto chromatin to form the pre-replication complex necessary to initiate DNA replication. Binds DNA in a sequence-, strand-, and conformation-independent manner. Potential oncogene.<ref>PMID:11850834</ref> <ref>PMID:12192004</ref> <ref>PMID:14993212</ref>
[https://www.uniprot.org/uniprot/CDT1_MOUSE CDT1_MOUSE] Cooperates with CDC6 to promote the loading of the mini-chromosome maintenance complex onto chromatin to form the pre-replication complex necessary to initiate DNA replication. Binds DNA in a sequence-, strand-, and conformation-independent manner. Potential oncogene.<ref>PMID:11850834</ref> <ref>PMID:12192004</ref> <ref>PMID:14993212</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 33: Line 33:
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Hanaoka, F]]
[[Category: Hanaoka F]]
[[Category: Hiroaki, H]]
[[Category: Hiroaki H]]
[[Category: Jee, J G]]
[[Category: Jee JG]]
[[Category: Kamada, K]]
[[Category: Kamada K]]
[[Category: Mizuno, T]]
[[Category: Mizuno T]]
[[Category: Shirakawa, M]]
[[Category: Shirakawa M]]
[[Category: Tochio, H]]
[[Category: Tochio H]]
[[Category: Cell cycle]]
[[Category: Dna replication]]
[[Category: Dna-binding]]
[[Category: Licensing factor]]
[[Category: Proto-oncogene]]
Retrieved from "https://proteopedia.org/2rqq"