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==Solution structure of the PDZ domain from mouse LIM domain kinase==
==Solution structure of the PDZ domain from mouse LIM domain kinase==
<StructureSection load='2yub' size='340' side='right'caption='[[2yub]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2yub' size='340' side='right'caption='[[2yub]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2yub]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YUB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YUB FirstGlance]. <br>
<table><tr><td colspan='2'>[[2yub]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YUB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YUB FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Limk2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yub OCA], [https://pdbe.org/2yub PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yub RCSB], [https://www.ebi.ac.uk/pdbsum/2yub PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yub ProSAT], [https://www.topsan.org/Proteins/RSGI/2yub TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yub OCA], [https://pdbe.org/2yub PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yub RCSB], [https://www.ebi.ac.uk/pdbsum/2yub PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yub ProSAT], [https://www.topsan.org/Proteins/RSGI/2yub TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/LIMK2_MOUSE LIMK2_MOUSE]] Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro (By similarity).  
[https://www.uniprot.org/uniprot/LIMK2_MOUSE LIMK2_MOUSE] Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Hayashi F]]
[[Category: Hayashi, F]]
[[Category: Suetake T]]
[[Category: Structural genomic]]
[[Category: Yokoyama S]]
[[Category: Suetake, T]]
[[Category: Yokoyama, S]]
[[Category: Limk-2]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Pdz domain]]
[[Category: Rsgi]]
[[Category: Transferase]]

Latest revision as of 19:18, 29 May 2024

Solution structure of the PDZ domain from mouse LIM domain kinase

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