NMR Ensembles of Models: Difference between revisions
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Model building for NMR experiments typically starts with the complete protein or nucleic acid chain, including [[Hydrogen in macromolecular models|hydrogen atoms]]. The distance restraints are then applied. The resulting model usually includes the entire protein and nucleic acid chains, unlike [[X-ray crystallography|X-ray crystallographic]] models that often lack the ends, and even loops in the middle of chains, due to [[Disorder|disorder]] in protein crystals. | Model building for NMR experiments typically starts with the complete protein or nucleic acid chain, including [[Hydrogen in macromolecular models|hydrogen atoms]]. The distance restraints are then applied. The resulting model usually includes the entire protein and nucleic acid chains, unlike [[X-ray crystallography|X-ray crystallographic]] models that often lack the ends, and even loops in the middle of chains, due to [[Disorder|disorder]] in protein crystals. | ||
Macromolecular structure determination by NMR is done at high protein concentrations in aqueous solution, and thus requires that the molecule be highly soluble. For more information, see | Macromolecular structure determination by NMR is done at high protein concentrations in aqueous solution, and thus requires that the molecule be highly soluble. For more information, see ''NMR in Wikipedia''<ref>[http://en.wikipedia.org/wiki/Nuclear_magnetic_resonance NMR in Wikipedia]</ref>. | ||
==Displaying NMR Models== | ==Displaying NMR Models== | ||
