Helicase: Difference between revisions

Line 3:

'''Helicase''' (Hel) is a motor protein which separates nucleic acid strands like DNA double helix or self-annealed RNA. They use ATP hydrolysis for energy. Hel falls into 5 superfamilies (SF1-SF5). Some Hel contain a Helicase and RNase D C terminal

Domain (HRDC). The α-thalassemia and mental retardation X-linked syndrome helicase (ATRX ), contains an ATRX-Dnmt3-Dnmt3L (ADD) domain in which many disease-related mutations are found.<br />

'''ATP-dependent helicase Rho''' is a protein involved in termination of transcription in prokaryotes. Rho binds to the transcription terminator site on single-stranded RNA. Rho forms a ring-shaped hexamer and advances along the mRNA until it reaches the RNA polymerase and causing it to dissociate from the DNA and end transcription.<br />

*'''ATP-dependent helicase Rho''' is a protein involved in termination of transcription in prokaryotes. Rho binds to the transcription terminator site on single-stranded RNA. Rho forms a ring-shaped hexamer and advances along the mRNA until it reaches the RNA polymerase and causing it to dissociate from the DNA and end transcription.<br />

'''ATP-dependent helicase RuvB-like 1''' (RuvBL1) or '''TIP49''' is a human protein which forms hexamers. The hexamer forms dodecamer upon association with RuvBL2 or '''TIP48''' and the complex possesses single-stranded DNA-stimulated ATPase and helicase activities.

*'''ATP-dependent helicase RuvB-like 1''' (RuvBL1) or '''TIP49''' is a human protein which forms hexamers. The hexamer forms dodecamer upon association with RuvBL2 or '''TIP48''' and the complex possesses single-stranded DNA-stimulated ATPase and helicase activities.

*'''DnaB''' exhibits helices and ATPase activities<ref>PMID:24387047</ref>.

For details of PcrA helicase see<br />

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 3: / Line 3: @@
 '''Helicase''' (Hel) is a motor protein which separates nucleic acid strands like DNA double helix or self-annealed RNA.  They use ATP hydrolysis for energy.  Hel falls into 5 superfamilies (SF1-SF5).  Some Hel contain a Helicase and RNase D C terminal
 Domain (HRDC).  The α-thalassemia and mental retardation X-linked syndrome helicase (ATRX ), contains an ATRX-Dnmt3-Dnmt3L (ADD) domain in which many disease-related mutations are found.<br />
-'''ATP-dependent helicase Rho''' is a protein involved in termination of transcription in prokaryotes.  Rho binds to the transcription terminator site on single-stranded RNA.  Rho forms a ring-shaped hexamer and advances along the mRNA until it reaches the RNA polymerase and causing it to dissociate from the DNA and end transcription.<br />
+*'''ATP-dependent helicase Rho''' is a protein involved in termination of transcription in prokaryotes.  Rho binds to the transcription terminator site on single-stranded RNA.  Rho forms a ring-shaped hexamer and advances along the mRNA until it reaches the RNA polymerase and causing it to dissociate from the DNA and end transcription.<br />
-'''ATP-dependent helicase RuvB-like 1''' (RuvBL1) or '''TIP49''' is a human protein which forms hexamers.  The hexamer forms dodecamer upon association with RuvBL2 or '''TIP48''' and the complex possesses single-stranded DNA-stimulated ATPase and helicase activities.
+*'''ATP-dependent helicase RuvB-like 1''' (RuvBL1) or '''TIP49''' is a human protein which forms hexamers.  The hexamer forms dodecamer upon association with RuvBL2 or '''TIP48''' and the complex possesses single-stranded DNA-stimulated ATPase and helicase activities.
+*'''DnaB''' exhibits helices and ATPase activities<ref>PMID:24387047</ref>.
 For details of PcrA helicase see<br />