Insulin: Difference between revisions
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'''Insulin''' is a peptide [[hormone]] that helps to maintain blood sugar within a healthy range by regulating [[Carbohydrate Metabolism|carbohydrate]] and lipid metabolism throughout the body. It is secreted by specialized cells in the pancreas and acts by binding to [[insulin receptor|insulin receptors]] on other cells. Insulin in its mature form contains two peptide chains connected by [[Cystine|disulfide crosslinks]], and occurs either as monomer or as hexamer. Administering insulin in carefully determined doses at the appropriate times is used in managing [[diabetes]], a chronic condition where the body fails to maintain blood sugar levels by itself. | '''Insulin''' is a peptide [[hormone]] that helps to maintain blood sugar within a healthy range by regulating [[Carbohydrate Metabolism|carbohydrate]] and lipid metabolism throughout the body. It is secreted by specialized cells in the pancreas and acts by binding to [[insulin receptor|insulin receptors]] on other cells. Insulin in its mature form contains two peptide chains connected by [[Cystine|disulfide crosslinks]], and occurs either as monomer or as hexamer. Administering insulin in carefully determined doses at the appropriate times is used in managing [[diabetes]], a chronic condition where the body fails to maintain blood sugar levels by itself. | ||
*'''Proinsulin''' is the insulin precursor which is converted in the pancreas to insulin and C-peptide<ref>PMID:403392</ref>. | |||
==Other Proteopedia pages about or relating to insulin== | ==Other Proteopedia pages about or relating to insulin== | ||
This page is for an audience with some basic knowledge of biochemistry. If you encounter terms you don't know, such as disulfide bond or hexamer, you are encouraged to look them up on Proteopedia or elsewhere. Sometimes, links are already provided, and sometimes a close look at the 3D figures will already give you an idea. Below are listed other pages on the topic, some more basic and some more detailed. | This page is for an audience with some basic knowledge of biochemistry. If you encounter terms you don't know, such as disulfide bond or hexamer, you are encouraged to look them up on Proteopedia or elsewhere. Sometimes, links are already provided, and sometimes a close look at the 3D figures will already give you an idea. Below are listed other pages on the topic, some more basic and some more detailed. | ||
