8uxs: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 8uxs is ~~ON HOLD~~

==KLHDC2 ubiquitin ligase in complex with a novel small-molecule==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[8uxs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8UXS OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=8UXS FirstGlance].

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=XU8:{4-[(2-{[(4-tert-butylphenyl)methyl]sulfanyl}acetamido)methyl]-1H-1,2,3-triazol-1-yl}acetic+acid'>XU8</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=8uxs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8uxs OCA], [https://pdbe.org/8uxs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8uxs RCSB], [https://www.ebi.ac.uk/pdbsum/8uxs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8uxs ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/KLDC2_HUMAN KLDC2_HUMAN] Represses CREB3-mediated transcription by interfering with CREB3-DNA binding.<ref>PMID:11384994</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Rusnac DV]]

[[Category: Zheng N]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 8uxs is ON HOLD
+==KLHDC2 ubiquitin ligase in complex with a novel small-molecule==
+<StructureSection load='8uxs' size='340' side='right'caption='[[8uxs]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8uxs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8UXS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8UXS FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=XU8:{4-[(2-{[(4-tert-butylphenyl)methyl]sulfanyl}acetamido)methyl]-1H-1,2,3-triazol-1-yl}acetic+acid'>XU8</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8uxs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8uxs OCA], [https://pdbe.org/8uxs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8uxs RCSB], [https://www.ebi.ac.uk/pdbsum/8uxs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8uxs ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/KLDC2_HUMAN KLDC2_HUMAN] Represses CREB3-mediated transcription by interfering with CREB3-DNA binding.<ref>PMID:11384994</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Rusnac DV]]
+[[Category: Zheng N]]