Outer surface protein: Difference between revisions
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<StructureSection load='2af5' size='350' side='right' caption='Outer surface protein A (PDB entry [[2af5]])' scene=''> | <StructureSection load='2af5' size='350' side='right' caption='Outer surface protein A (PDB entry [[2af5]])' scene=''> | ||
'''Outer surface proteins''' (Osp) are produced by the bacteria Borrelia burgdorferi which causes Lyme disease. OspA and OspB are upregulated when the bacteria enter the tick. *'''OspA'''<ref>PMID:10953031</ref> contributes to the colonization of the gut by the bacteria. | '''Outer surface proteins''' (Osp) are produced by the bacteria Borrelia burgdorferi which causes Lyme disease. OspA and OspB are upregulated when the bacteria enter the tick. | ||
*'''OspA'''<ref>PMID:10953031</ref> contributes to the colonization of the gut by the bacteria. | |||
* '''OspB'''<ref>PMID:17352535</ref>, '''OspC'''<ref>PMID:26438793</ref> and '''OspE'''<ref>PMID:8262642</ref> are major antigens on the surface of the Lyme disease spirochetes when it is being transmitted to humans. For more details see:<br /> | * '''OspB'''<ref>PMID:17352535</ref>, '''OspC'''<ref>PMID:26438793</ref> and '''OspE'''<ref>PMID:8262642</ref> are major antigens on the surface of the Lyme disease spirochetes when it is being transmitted to humans. For more details see:<br /> | ||
OspA - <br /> | OspA - <br /> | ||
