8k3o: Difference between revisions
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==Cryo-EM structure of 30S ribosome with cleaved AP-mRNA bound complex I== | |||
<StructureSection load='8k3o' size='340' side='right'caption='[[8k3o]], [[Resolution|resolution]] 3.88Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8k3o]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8K3O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8K3O FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.88Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=N:ANY+5-MONOPHOSPHATE+NUCLEOTIDE'>N</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8k3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8k3o OCA], [https://pdbe.org/8k3o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8k3o RCSB], [https://www.ebi.ac.uk/pdbsum/8k3o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8k3o ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RS5_ECOLI RS5_ECOLI] With S4 and S12 plays an important role in translational accuracy. Many suppressors of streptomycin-dependent mutants of protein S12 are found in this protein, some but not all of which decrease translational accuracy (ram, ribosomal ambiguity mutations).<ref>PMID:15652481</ref> Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.<ref>PMID:15652481</ref> The physical location of this protein suggests it may also play a role in mRNA unwinding by the ribosome, possibly by forming part of a processivity clamp.<ref>PMID:15652481</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli K-12]] | |||
[[Category: Large Structures]] | |||
[[Category: Afsar M]] | |||
[[Category: Ramachandran R]] | |||
[[Category: Shukla A]] | |||
Latest revision as of 06:30, 24 July 2024
Cryo-EM structure of 30S ribosome with cleaved AP-mRNA bound complex I
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