8ptt: Difference between revisions
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==Human NUDT5 in complex with MRK-952== | |||
<StructureSection load='8ptt' size='340' side='right'caption='[[8ptt]], [[Resolution|resolution]] 2.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8ptt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PTT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8PTT FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F2V:6-[(5~{R})-7-[3-chloranyl-4-(trifluoromethyl)phenyl]-2,7-diazaspiro[4.4]nonan-2-yl]-7-methyl-purine'>F2V</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ptt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ptt OCA], [https://pdbe.org/8ptt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ptt RCSB], [https://www.ebi.ac.uk/pdbsum/8ptt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ptt ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/NUDT5_HUMAN NUDT5_HUMAN] Hydrolyzes with similar activities ADP-ribose ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP. Can also hydrolyze other nucleotide sugars with low activity.<ref>PMID:17052728</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Arrowsmith CH]] | |||
[[Category: Bountra C]] | |||
[[Category: Diaz-Saez L]] | |||
[[Category: Edwards AM]] | |||
[[Category: Feyerherm C]] | |||
[[Category: Fischer C]] | |||
[[Category: Huber KVM]] | |||
[[Category: Koekemoer L]] | |||
[[Category: Schneider S]] | |||
[[Category: Sloman S]] | |||
[[Category: Von Delft F]] | |||
Latest revision as of 06:31, 24 July 2024
Human NUDT5 in complex with MRK-952
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