9ija: Difference between revisions

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'''Unreleased structure'''


The entry 9ija is ON HOLD
==A local Cryo-EM structure of Bitter taste receptor TAS2R14 with Gi complex==
 
<StructureSection load='9ija' size='340' side='right'caption='[[9ija]], [[Resolution|resolution]] 3.05&Aring;' scene=''>
Authors: Yuan, Q., Duan, J., Tao, L., Xu, E.H.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9ija]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9IJA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9IJA FirstGlance]. <br>
Description: A local Cryo-EM structure of Bitter taste receptor TAS2R14 with Gi complex
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.05&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1AEI:4-methyl-N-[(2M)-2-(1H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)pyrimidin-2-amine'>A1AEI</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene></td></tr>
[[Category: Yuan, Q]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ija FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ija OCA], [https://pdbe.org/9ija PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ija RCSB], [https://www.ebi.ac.uk/pdbsum/9ija PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ija ProSAT]</span></td></tr>
[[Category: Tao, L]]
</table>
[[Category: Duan, J]]
== Function ==
[[Category: Xu, E.H]]
[https://www.uniprot.org/uniprot/T2R14_HUMAN T2R14_HUMAN] Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Duan J]]
[[Category: Tao L]]
[[Category: Xu EH]]
[[Category: Yuan Q]]