ConSurfDB vs. ConSurf: Difference between revisions
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==Examples== | ==Examples== | ||
<StructureSection load='' size='350' side='right' caption='' scene='39/399854/2vaa_consurf_halos_w274_y159/4'> | <StructureSection load='' size='350' side='right' caption='' scene='39/399854/2vaa_consurf_halos_w274_y159/4'> | ||
With default parameters, the ConSurf Server results have an average [[#Average Pairwise Distance]] (APD) of 1.00<ref name="APD">Tested with 20 arbitrarily selected proteins, mostly enzymes. Average of the average pairwise distance (APD) values: 1.00; range 0.82-1.42.</ref>, and an average of only a few "yellow" residues with insufficient data.<ref name="ISD">Tested with 20 arbitrarily selected proteins, mostly enzymes. Average number of amino acids with insufficient data ("yellow" in ConSurf): 3.5; range 0 to 16.</ref> For the examples below, it was necessary to [[#Limiting ConSurf Analysis to Proteins of a Single Function|customize the ConSurf Server job parameters]] in order to reveal conservation | With default parameters, the ConSurf Server results have an average [[#Average Pairwise Distance]] (APD) of 1.00<ref name="APD">Tested with 20 arbitrarily selected proteins, mostly enzymes. Average of the average pairwise distance (APD) values: 1.00; range 0.82-1.42.</ref>, and an average of only a few "yellow" residues with insufficient data.<ref name="ISD">Tested with 20 arbitrarily selected proteins, mostly enzymes. Average number of amino acids with insufficient data ("yellow" in ConSurf): 3.5; range 0 to 16.</ref> For the examples below, it was necessary to [[#Limiting ConSurf Analysis to Proteins of a Single Function|customize the ConSurf Server job parameters]] in order to '''reveal conservation of key residues''' in proteins with the same function as the query. | ||
These molecular scenes were obtained in [[FirstGlance in Jmol]], which offers many conveniences for analyzing ConSurf Server results. See [[Help:How to Insert a ConSurf Result Into a Proteopedia Green Link|How to Insert a ConSurf Result Into a Proteopedia Green Link]]. | These molecular scenes were obtained in [[FirstGlance in Jmol]], which offers many conveniences for analyzing ConSurf Server results. See [[Help:How to Insert a ConSurf Result Into a Proteopedia Green Link|How to Insert a ConSurf Result Into a Proteopedia Green Link]]. | ||