8y86: Difference between revisions
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The entry | ==Human AE3 with NaHCO3-== | ||
<StructureSection load='8y86' size='340' side='right'caption='[[8y86]], [[Resolution|resolution]] 2.75Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8y86]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Y86 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Y86 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.75Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8y86 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8y86 OCA], [https://pdbe.org/8y86 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8y86 RCSB], [https://www.ebi.ac.uk/pdbsum/8y86 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8y86 ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/B3A3_HUMAN B3A3_HUMAN] Familial short QT syndrome. The disease is caused by variants affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/B3A3_HUMAN B3A3_HUMAN] Sodium-independent anion exchanger which mediates the electroneutral exchange of chloride for bicarbonate ions across the cell membrane (PubMed:29167417, PubMed:7923606). May be involved in the regulation of intracellular pH, and the modulation of cardiac action potential (PubMed:29167417).<ref>PMID:29167417</ref> <ref>PMID:7923606</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Cao Y]] | |||
[[Category: Jian L]] | |||
[[Category: Yao D]] | |||
[[Category: Zhang Q]] | |||
