9atw: Difference between revisions
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==Structure of biofilm-forming functional amyloid PSMa1 from Staphylococcus aureus== | |||
<StructureSection load='9atw' size='340' side='right'caption='[[9atw]], [[Resolution|resolution]] 3.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9atw]] is a 64 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9ATW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9ATW FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.5Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9atw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9atw OCA], [https://pdbe.org/9atw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9atw RCSB], [https://www.ebi.ac.uk/pdbsum/9atw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9atw ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PSMA1_STAAW PSMA1_STAAW] Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection. Stimulates the secretion of the chemotactic factor interleukin-8 (IL-8). The ensuing activation process triggers an inflammatory response in the host, thus contributing greatly to virulence. Also possesses hemolytic activity, which may contribute to the development of disease.<ref>PMID:17994102</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Staphylococcus aureus]] | |||
[[Category: Akbey U]] | |||
[[Category: Andreasen M]] | |||
[[Category: Boesen T]] | |||
[[Category: Byeon CH]] | |||
[[Category: Conway JF]] | |||
[[Category: Drace T]] | |||
[[Category: Hansen KH]] | |||
[[Category: Liu Q]] | |||
Latest revision as of 05:44, 7 August 2024
Structure of biofilm-forming functional amyloid PSMa1 from Staphylococcus aureus
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