8tr5: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 8tr5 is ~~ON HOLD until Paper Publication~~

==Cryo-EM structure of the rat P2X7 receptor in the apo closed state==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[8tr5]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus Rattus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TR5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TR5 FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.53Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8tr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8tr5 OCA], [https://pdbe.org/8tr5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8tr5 RCSB], [https://www.ebi.ac.uk/pdbsum/8tr5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8tr5 ProSAT]</span></td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/P2RX7_RAT P2RX7_RAT] Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Rattus]]

[[Category: Glasfeld A]]

[[Category: Godsey MH]]

[[Category: Krishnamurthy I]]

[[Category: Lisi NE]]

[[Category: Mansoor SE]]

[[Category: McCarthy AE]]

[[Category: Oken AC]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 8tr5 is ON HOLD  until Paper Publication
+==Cryo-EM structure of the rat P2X7 receptor in the apo closed state==
+<StructureSection load='8tr5' size='340' side='right'caption='[[8tr5]], [[Resolution|resolution]] 2.53&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8tr5]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus Rattus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TR5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TR5 FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.53&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8tr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8tr5 OCA], [https://pdbe.org/8tr5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8tr5 RCSB], [https://www.ebi.ac.uk/pdbsum/8tr5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8tr5 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/P2RX7_RAT P2RX7_RAT] Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Rattus]]
+[[Category: Glasfeld A]]
+[[Category: Godsey MH]]
+[[Category: Krishnamurthy I]]
+[[Category: Lisi NE]]
+[[Category: Mansoor SE]]
+[[Category: McCarthy AE]]
+[[Category: Oken AC]]