Synapsin

spinqualitylabelsall models Rat synapsin 1 complex with ATP and Ca++ ion (green) (PDB code 1px2) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Synapsins (SYN) are neuronal phosphoproteins which modulate neurotransmitter release at the pre-synaptic terminal by reversibly tethering synaptic vescicles to the actin cytoskeleton. Synapsin 1 is involved in synapse formation. Synapsin 2 is involved in axon formation Structural highlights The 3D structure of the rat synapsin 1 complex with ATP shows the catalytically essential multifunctional loop surrounding the ATP which makes both hydrogen bonds and Van-der Waals contacts with the protein. Water molecules are shown as red spheres. 3D structures of synapsin Updated on 15-August-2024 {"openlevels":0} Synapsin 1 1auv - bSYN1A C-terminal 110-421 - bovine 1aux - bSYN1A C-terminal + ATPgS 1pk8, 1px2 - rSYN1 + ATP - rat Synapsin 2 1i7n - rSYN2 C-terminal 1i7l - rSYN2 C-terminal + ATP Synapsin 3 2p0a - hSYN3 actin-binding+synaptic vescicle binding domains 76-417 + AMPPNP - human

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