Syntaxin: Difference between revisions
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*'''Stx-1''' is essential for the formation of the SNARE complex involved in the fusion machinery in the brain. Stx-1 forms a 4-helical bundle complex with proteins SNAP-25 and VAMP2 which drives fusion of vesicles with the plasma membrane<ref>PMID:26903802</ref>. The coiled-coil bundle structure is formed by the interactions of the complex SNARE motifs<ref>PMID:24218570</ref>. | *'''Stx-1''' is essential for the formation of the SNARE complex involved in the fusion machinery in the brain. Stx-1 forms a 4-helical bundle complex with proteins SNAP-25 and VAMP2 which drives fusion of vesicles with the plasma membrane<ref>PMID:26903802</ref>. The coiled-coil bundle structure is formed by the interactions of the complex SNARE motifs<ref>PMID:24218570</ref>. | ||
*'''Stx-1A''' regulates the function of transmembrane proteins like ion channels and neurotransmitter transporters<ref>PMID:18617632</ref>. | *'''Stx-1A''' regulates the function of transmembrane proteins like ion channels and neurotransmitter transporters<ref>PMID:18617632</ref>. | ||
*'''Stx-6''' is a SNARE protein involved in a variety of internal membrane fusion events. | |||
*'''Stx-7''' is involved in endosomal membrane fusion<ref>PMID:34408265</ref>. | |||
== Relevance == | == Relevance == | ||
