8tft: Difference between revisions

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'''Unreleased structure'''


The entry 8tft is ON HOLD  until Paper Publication
==Fab of O13-1 human IgG1 antibody bound to IgV domain of human TIM-3==
 
<StructureSection load='8tft' size='340' side='right'caption='[[8tft]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
Authors: Oganesyan, V.Y., van Dyk, N., Mazor, Y., Yang, C.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8tft]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TFT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TFT FirstGlance]. <br>
Description: Fab of O13-1 human IgG1 antibody bound to IgV domain of human TIM-3
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8tft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8tft OCA], [https://pdbe.org/8tft PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8tft RCSB], [https://www.ebi.ac.uk/pdbsum/8tft PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8tft ProSAT]</span></td></tr>
[[Category: Yang, C]]
</table>
[[Category: Oganesyan, V.Y]]
== Function ==
[[Category: Van Dyk, N]]
[https://www.uniprot.org/uniprot/HAVR2_HUMAN HAVR2_HUMAN] Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Receptor for LGALS9.<ref>PMID:14556005</ref> <ref>PMID:16286920</ref>
[[Category: Mazor, Y]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Mazor Y]]
[[Category: Oganesyan VY]]
[[Category: Yang C]]
[[Category: Van Dyk N]]
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