8tzi: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Human equilibrative nucleoside transporter-1, JH-ENT-01 bound== | |||
<StructureSection load='8tzi' size='340' side='right'caption='[[8tzi]], [[Resolution|resolution]] 2.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8tzi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TZI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TZI FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8tzi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8tzi OCA], [https://pdbe.org/8tzi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8tzi RCSB], [https://www.ebi.ac.uk/pdbsum/8tzi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8tzi ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/S29A1_HUMAN S29A1_HUMAN] Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and dilazep (anticancer chemotherapeutics drugs). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Lee SY]] | |||
[[Category: Wright NJ]] | |||
Latest revision as of 05:22, 28 August 2024
Human equilibrative nucleoside transporter-1, JH-ENT-01 bound
| ||||||||||||
