8pef: Difference between revisions

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'''Unreleased structure'''


The entry 8pef is ON HOLD  until Paper Publication
==Crystal structure of SLF1 Ankyrin repeat domain in complex with H4 tail (K20me0)==
 
<StructureSection load='8pef' size='340' side='right'caption='[[8pef]], [[Resolution|resolution]] 1.28&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8pef]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PEF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8PEF FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.28&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8pef FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8pef OCA], [https://pdbe.org/8pef PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8pef RCSB], [https://www.ebi.ac.uk/pdbsum/8pef PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8pef ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SLF1_HUMAN SLF1_HUMAN] Plays a role in the DNA damage response (DDR) pathway by regulating postreplication repair of UV-damaged DNA and genomic stability maintenance (PubMed:25931565). The SLF1-SLF2 complex acts to link RAD18 with the SMC5-SMC6 complex at replication-coupled interstrand cross-links (ICL) and DNA double-strand breaks (DSBs) sites on chromatin during DNA repair in response to stalled replication forks (PubMed:25931565). Promotes the recruitment of SLF2 and the SMC5-SMC6 complex to DNA lesions (PubMed:25931565, PubMed:36373674).<ref>PMID:25931565</ref> <ref>PMID:36373674</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Nasir N]]
[[Category: Ryder EL]]
[[Category: Wu Q]]
Retrieved from "https://proteopedia.org/8pef"