2kv3: Difference between revisions

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==Human Regenerating Gene Type IV (REG IV) PROTEIN, P91S mutant==
==Human Regenerating Gene Type IV (REG IV) PROTEIN, P91S mutant==
<StructureSection load='2kv3' size='340' side='right'caption='[[2kv3]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2kv3' size='340' side='right'caption='[[2kv3]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2kv3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KV3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KV3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2kv3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KV3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KV3 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">REG4 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kv3 OCA], [https://pdbe.org/2kv3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kv3 RCSB], [https://www.ebi.ac.uk/pdbsum/2kv3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kv3 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kv3 OCA], [https://pdbe.org/2kv3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kv3 RCSB], [https://www.ebi.ac.uk/pdbsum/2kv3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kv3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/REG4_HUMAN REG4_HUMAN]] Calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment. May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium.<ref>PMID:12819006</ref> <ref>PMID:20692269</ref>
[https://www.uniprot.org/uniprot/REG4_HUMAN REG4_HUMAN] Calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment. May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium.<ref>PMID:12819006</ref> <ref>PMID:20692269</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kv/2kv3_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kv/2kv3_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Chen, C]]
[[Category: Chen C]]
[[Category: Ho, M]]
[[Category: Ho M]]
[[Category: Lou, Y]]
[[Category: Lou Y]]
[[Category: C-type lectin]]
[[Category: Disulfide bond]]
[[Category: Gisp]]
[[Category: Glycoprotein]]
[[Category: Lectin]]
[[Category: Reg 4]]
[[Category: Reg iv]]
[[Category: Secreted]]
[[Category: Sugar binding protein]]