3t7d: Difference between revisions

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<StructureSection load='3t7d' size='340' side='right'caption='[[3t7d]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='3t7d' size='340' side='right'caption='[[3t7d]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3t7d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"streptomyces_hygroscopicus_subsp._limoneus"_shibata_et_al._1973 "streptomyces hygroscopicus subsp. limoneus" shibata et al. 1973]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T7D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T7D FirstGlance]. <br>
<table><tr><td colspan='2'>[[3t7d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_hygroscopicus_subsp._limoneus Streptomyces hygroscopicus subsp. limoneus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T7D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T7D FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PRD_900006:trehalose'>PRD_900006</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3t5r|3t5r]], [[3t5t|3t5t]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">vldE ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=264445 "Streptomyces hygroscopicus subsp. limoneus" Shibata et al. 1973])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t7d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t7d OCA], [https://pdbe.org/3t7d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t7d RCSB], [https://www.ebi.ac.uk/pdbsum/3t7d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t7d ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t7d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t7d OCA], [https://pdbe.org/3t7d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t7d RCSB], [https://www.ebi.ac.uk/pdbsum/3t7d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t7d ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/VLDE_STRHL VLDE_STRHL] Involved in the biosynthesis of the antifungal agent validamycin A (PubMed:16725283). Catalyzes the condensation between GDP-valienol and validamine 7-phosphate via a nonglycosidic C-N bond formation to yield validoxylamine A 7'-phosphate (PubMed:21766819).<ref>PMID:16725283</ref> <ref>PMID:21766819</ref>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Streptomyces hygroscopicus subsp. limoneus shibata et al. 1973]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Chen, J]]
[[Category: Streptomyces hygroscopicus subsp. limoneus]]
[[Category: Qian, H]]
[[Category: Chen J]]
[[Category: Zhang, H]]
[[Category: Qian H]]
[[Category: Zheng, L]]
[[Category: Zhang H]]
[[Category: Gtb]]
[[Category: Zheng L]]
[[Category: Transferase]]

Latest revision as of 06:11, 17 October 2024

Vall from streptomyces hygroscopicus in complex with trehalose

3t7d, resolution 1.70Å

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