3uxu: Difference between revisions
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<StructureSection load='3uxu' size='340' side='right'caption='[[3uxu]], [[Resolution|resolution]] 2.71Å' scene=''> | <StructureSection load='3uxu' size='340' side='right'caption='[[3uxu]], [[Resolution|resolution]] 2.71Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3uxu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[3uxu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfolobus_spindle-shaped_virus_1 Sulfolobus spindle-shaped virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UXU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UXU FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.706Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uxu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uxu OCA], [https://pdbe.org/3uxu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uxu RCSB], [https://www.ebi.ac.uk/pdbsum/3uxu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uxu ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uxu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uxu OCA], [https://pdbe.org/3uxu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uxu RCSB], [https://www.ebi.ac.uk/pdbsum/3uxu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uxu ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/VINT_SSV1 VINT_SSV1] This protein may encode a site-specific integrase, which is necessary for integration of the phage by site-specific recombination into a tRNA gene of the host chromosome. Essential for virus infection.<ref>PMID:10430570</ref> <ref>PMID:22683788</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Sulfolobus spindle-shaped virus 1]] | ||
[[Category: Eilers | [[Category: Eilers BJ]] | ||
[[Category: Lawrence | [[Category: Lawrence CM]] | ||
[[Category: Young | [[Category: Young MJ]] | ||
Latest revision as of 06:15, 17 October 2024
The structure of the catalytic domain of the Sulfolobus Spindle-shaped viral integrase reveals an evolutionarily conserved catalytic core and supports a mechanism of DNA cleavage in trans
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