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==Plasmodium falciparum 6-phosphogluconate dehydrogenase in its apo form, in complex with its cofactor NADP+ and in complex with its substrate 6-phosphogluconate==
==Plasmodium falciparum 6-phosphogluconate dehydrogenase in its apo form, in complex with its cofactor NADP+ and in complex with its substrate 6-phosphogluconate==
<StructureSection load='6fqy' size='340' side='right' caption='[[6fqy]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='6fqy' size='340' side='right'caption='[[6fqy]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6fqy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plaf7 Plaf7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FQY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FQY FirstGlance]. <br>
<table><tr><td colspan='2'>[[6fqy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FQY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6FQY FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6fqz|6fqz]], [[6fqx|6fqx]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PF14_0520, PF3D7_1454700 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=36329 PLAF7])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6fqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fqy OCA], [https://pdbe.org/6fqy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6fqy RCSB], [https://www.ebi.ac.uk/pdbsum/6fqy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6fqy ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphogluconate_dehydrogenase_(NADP(+)-dependent,_decarboxylating) Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.44 1.1.1.44] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fqy OCA], [http://pdbe.org/6fqy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fqy RCSB], [http://www.ebi.ac.uk/pdbsum/6fqy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fqy ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/Q8IKT2_PLAF7 Q8IKT2_PLAF7]] Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.[PIRNR:PIRNR000109]  
[https://www.uniprot.org/uniprot/Q8IKT2_PLAF7 Q8IKT2_PLAF7] Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.[PIRNR:PIRNR000109]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6fqy" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6fqy" style="background-color:#fffaf0;"></div>
==See Also==
*[[6-phosphogluconate dehydrogenase 3D structures|6-phosphogluconate dehydrogenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Plaf7]]
[[Category: Large Structures]]
[[Category: Becker, K]]
[[Category: Plasmodium falciparum 3D7]]
[[Category: Fritz-Wolf, K]]
[[Category: Becker K]]
[[Category: Haeussler, K]]
[[Category: Fritz-Wolf K]]
[[Category: Rahlfs, S]]
[[Category: Haeussler K]]
[[Category: Reichmann, M]]
[[Category: Rahlfs S]]
[[Category: Complex]]
[[Category: Reichmann M]]
[[Category: Oxidoreductase]]
[[Category: Plasmodium]]
[[Category: Redoxregulation]]
[[Category: Substrate]]
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