1tl8: Difference between revisions

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[[Image:1tl8.gif|left|200px]]
[[Image:1tl8.gif|left|200px]]


{{Structure
<!--
|PDB= 1tl8 |SIZE=350|CAPTION= <scene name='initialview01'>1tl8</scene>, resolution 3.10&Aring;
The line below this paragraph, containing "STRUCTURE_1tl8", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
|LIGAND= <scene name='pdbligand=AI3:2,3-DIMETHOXY-12H-[1,3]DIOXOLO[5,6]INDENO[1,2-C]ISOQUINOLIN-6-IUM'>AI3</scene>, <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene>, <scene name='pdbligand=TPC:5&#39;-THIO-2&#39;-DEOXY-CYTOSINE+PHOSPHONIC+ACID'>TPC</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase DNA topoisomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.2 5.99.1.2] </span>
or leave the SCENE parameter empty for the default display.
|GENE= TOP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
-->
|DOMAIN=
{{STRUCTURE_1tl8|  PDB=1tl8 |  SCENE= }}  
|RELATEDENTRY=[[1k4t|1K4t]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tl8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tl8 OCA], [http://www.ebi.ac.uk/pdbsum/1tl8 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1tl8 RCSB]</span>
}}


'''Human DNA topoisomerase I (70 kDa) in complex with the indenoisoquinoline AI-III-52 and covalent complex with a 22 base pair DNA duplex'''
'''Human DNA topoisomerase I (70 kDa) in complex with the indenoisoquinoline AI-III-52 and covalent complex with a 22 base pair DNA duplex'''
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[[Category: Staker, B L.]]
[[Category: Staker, B L.]]
[[Category: Stewart, L.]]
[[Category: Stewart, L.]]
[[Category: complex (isomerase/dna)]]
[[Category: Dna]]
[[Category: dna]]
[[Category: Drug]]
[[Category: drug]]
[[Category: Idenoisoquinoline]]
[[Category: idenoisoquinoline]]
[[Category: Poison]]
[[Category: poison]]
[[Category: Topoisomerase i]]
[[Category: topoisomerase i]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 10:05:15 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:57:37 2008''
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