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<StructureSection load='7ngb' size='340' side='right'caption='[[7ngb]], [[Resolution|resolution]] 3.64&Aring;' scene=''>
<StructureSection load='7ngb' size='340' side='right'caption='[[7ngb]], [[Resolution|resolution]] 3.64&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[7ngb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NGB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NGB FirstGlance]. <br>
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NGB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NGB FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.64&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SLC12A6, KCC3 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ngb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ngb OCA], [https://pdbe.org/7ngb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ngb RCSB], [https://www.ebi.ac.uk/pdbsum/7ngb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ngb ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ngb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ngb OCA], [https://pdbe.org/7ngb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ngb RCSB], [https://www.ebi.ac.uk/pdbsum/7ngb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ngb ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
[[https://www.uniprot.org/uniprot/S12A6_HUMAN S12A6_HUMAN]] Corpus callosum agenesis-neuronopathy syndrome. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[[https://www.uniprot.org/uniprot/S12A6_HUMAN S12A6_HUMAN]] Mediates electroneutral potassium-chloride cotransport. May be activated by cell swelling. May contribute to cell volume homeostasis in single cells.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 7ngb" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 7ngb" style="background-color:#fffaf0;"></div>
==See Also==
*[[Solute carrier family 12 3D structures|Solute carrier family 12 3D structures]]
*[[Symporter 3D structures|Symporter 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Abrusci, P]]
[[Category: Abrusci P]]
[[Category: Arrowsmith, C H]]
[[Category: Arrowsmith CH]]
[[Category: Bountra, C]]
[[Category: Bountra C]]
[[Category: Burgess-Brown, N A]]
[[Category: Burgess-Brown NA]]
[[Category: Chalk, R]]
[[Category: Chalk R]]
[[Category: Chi, G]]
[[Category: Chi G]]
[[Category: Duerr, K L]]
[[Category: Duerr KL]]
[[Category: Edwards, A M]]
[[Category: Edwards AM]]
[[Category: MacLean, E M]]
[[Category: MacLean EM]]
[[Category: Man, H]]
[[Category: Man H]]
[[Category: Marsden, B D]]
[[Category: Marsden BD]]
[[Category: McKinley, G]]
[[Category: McKinley G]]
[[Category: Moreau, C]]
[[Category: Moreau C]]
[[Category: Mukhopadhyay, S M.M]]
[[Category: Mukhopadhyay SMM]]
[[Category: Pike, A C.W]]
[[Category: Pike ACW]]
[[Category: Snee, M]]
[[Category: Snee M]]
[[Category: Wang, D]]
[[Category: Wang D]]
[[Category: Ccc]]
[[Category: Homodimer]]
[[Category: Human membrane protein]]
[[Category: Kcc]]
[[Category: Kcc3]]
[[Category: Potassium-chloride coupled transporter]]
[[Category: Sgc]]
[[Category: Structural genomic]]
[[Category: Transport protein]]
[[Category: Transporter]]

Latest revision as of 09:00, 17 October 2024

Structure of Wild-Type Human Potassium Chloride Transporter KCC3 in NaCl (LMNG/CHS)

7ngb, resolution 3.64Å

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